Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models.

This study reports on the development of a liposomal formulation of vincristine with significantly enhanced stability and biological properties. The in vitro and in vivo pharmacokinetic, tumour delivery and efficacy properties of liposomal vincristine formulations based on sphingomyelin (SM) and cho...

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Autori principali: Webb, M. S., Harasym, T. O., Masin, D., Bally, M. B., Mayer, L. D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1995
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034038/
https://ncbi.nlm.nih.gov/pubmed/7547237
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