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Pharmacology of liposomal vincristine in mice bearing L1210 ascitic and B16/BL6 solid tumours.

Vincristine pharmacokinetic, tumour uptake and therapeutic characteristics were investigated here in order to elucidate the processes underlying the enhanced efficacy observed for vincristine entrapped in small (120 nm) distearoylphosphatidylcholine/cholesterol liposomes. Plasma vincristine levels a...

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Autors principals: Mayer, L. D., Masin, D., Nayar, R., Boman, N. L., Bally, M. B.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033637/
https://ncbi.nlm.nih.gov/pubmed/7880728
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