Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas--relationship to amplification and mRNA levels of CDK4 and CCND1.

Homozygous deletions of the putative tumour-suppressor gene CDKN2, which encodes an inhibitor of cdk4, have been detected in a high percentage of cancer cell lines of various histological types. In the present study, 109 human sarcomas were examined for homozygous deletions and for mRNA expression l...

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Hlavní autoři: Maelandsmo, G. M., Berner, J. M., Flørenes, V. A., Forus, A., Hovig, E., Fodstad, O., Myklebost, O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1995
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033985/
https://ncbi.nlm.nih.gov/pubmed/7640224
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