Expression of multidrug resistance-associated protein (MRP), MDR1 and DNA topoisomerase II in human multidrug-resistant bladder cancer cell lines.

The acquisition of the multidrug resistance phenotype in human tumours is associated with an overexpression of the 170 kDa P-glycoprotein encoded by the multidrug resistance 1 (MDR1) gene, and also with a 190 kDa membrane ATP-binding protein encoded by a multidrug resistance-associated protein (MRP)...

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Autors principals: Hasegawa, S., Abe, T., Naito, S., Kotoh, S., Kumazawa, J., Hipfner, D. R., Deeley, R. G., Cole, S. P., Kuwano, M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033770/
https://ncbi.nlm.nih.gov/pubmed/7734314
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