Chemosensitisation of spontaneous multidrug resistance by a 1,4-dihydropyridine analogue and verapamil in human glioma cell lines overexpressing MRP or MDR1.

Multidrug resistance phenotypes in human tumours are associated with the overexpression of the 170 kDa P-glycoprotein encoded by the multidrug resistance 1 (MDR1) gene, and also with that of the non-P-glycoprotein-mediated multidrug resistance gene, MRP, which encodes a 190 kDa membrane ATP-binding...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Abe, T., Koike, K., Ohga, T., Kubo, T., Wada, M., Kohno, K., Mori, T., Hidaka, K., Kuwano, M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1995
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033970/
https://ncbi.nlm.nih.gov/pubmed/7640227
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi