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The interaction with tubulin of a series of stilbenes based on combretastatin A-4.

A series of stilbenes, based on combretastatin A-4, were synthesised. A structure-activity study was carried out to characterise the interaction of these agents with tubulin. The substitution of small alkyl substituents for the 4'-methoxy group of combretastatin A-4 and the loss of the 3'-...

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Main Authors: Woods, J. A., Hadfield, J. A., Pettit, G. R., Fox, B. W., McGown, A. T.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033763/
https://ncbi.nlm.nih.gov/pubmed/7710932
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