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A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1
The 90 kDa ribosomal S6 kinase-2 (RSK2) is a growth factor-stimulated protein kinase with two kinase domains. The C-terminal kinase of RSK2 is activated by ERK-type MAP kinases, leading to autophosphorylation of RSK2 at Ser386 in a hydrophobic motif. The N-terminal kinase is activated by 3-phosphoin...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC203368/ https://ncbi.nlm.nih.gov/pubmed/10856237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.12.2924 |
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