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Three telomerases with completely non-telomeric template replacements are catalytically active
Telomerase is a reverse transcriptase minimally composed of a reverse transcriptase protein subunit and an internal RNA component that contains the templating region. Point mutations of template RNA bases can cause loss of enzymatic activity, reduced processivity and misincorporation in vitro. Here...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC203363/ https://ncbi.nlm.nih.gov/pubmed/10856255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.12.3119 |
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