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An antiapoptotic role for telomerase RNA in human immune cells independent of telomere integrity or telomerase enzymatic activity

Telomerase is a ribonucleoprotein complex that adds telomeric DNA to the ends of linear chromosomes. It contains two core canonical components: the essential RNA component, hTR, which provides the template for DNA synthesis, and the reverse transcriptase protein component, hTERT. Low telomerase acti...

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Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Gazzaniga, Francesca S., Blackburn, Elizabeth H.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263978/
https://ncbi.nlm.nih.gov/pubmed/25320237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-582254
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