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Three telomerases with completely non-telomeric template replacements are catalytically active
Telomerase is a reverse transcriptase minimally composed of a reverse transcriptase protein subunit and an internal RNA component that contains the templating region. Point mutations of template RNA bases can cause loss of enzymatic activity, reduced processivity and misincorporation in vitro. Here...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2000
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC203363/ https://ncbi.nlm.nih.gov/pubmed/10856255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.12.3119 |
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