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Separate domains in E1 and E2 proteins serve architectural and productive roles for cooperative DNA binding
The E1 and E2 proteins from bovine papillomavirus bind cooperatively to binding sites in the viral origin of DNA replication. The DNA-binding domains (DBDs) of the two proteins interact with each other, and the E2 transactivation domain interacts with the helicase domain of E1. Mutations that disrup...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2000
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC203343/ https://ncbi.nlm.nih.gov/pubmed/10856250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.12.3069 |
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