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E1 initiator DNA binding specificity is unmasked by selective inhibition of non-specific DNA binding

Initiator proteins are critical components of the DNA replication machinery and mark the site of initiation. This activity probably requires highly selective DNA binding; however, many initiators display modest specificity in vitro. We demonstrate that low specificity of the papillomavirus E1 initia...

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Detalhes bibliográficos
Autor principal: Stenlund, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC145451/
https://ncbi.nlm.nih.gov/pubmed/12574131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg091
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