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The Evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death

Evi-1 encodes a nuclear protein involved in leukemic transformation of hematopoietic cells. Evi-1 possesses two sets of zinc finger motifs separated into two domains, and its characteristics as a transcriptional regulator have been described. Here we show that Evi-1 acts as an inhibitor of c-Jun N-t...

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Udgivet i:EMBO J
Principais autores: Kurokawa, Mineo, Mitani, Kinuko, Yamagata, Tetsuya, Takahashi, Tokiharu, Izutsu, Koji, Ogawa, Seishi, Moriguchi, Tetsuo, Nishida, Eisuke, Yazaki, Yoshio, Hirai, Hisamaru
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2000
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203342/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10856240/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.12.2958
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