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SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55

Src-homology 3 (SH3) domains recognize PXXP core motif preceded or followed by positively charged residue(s). Whether SH3 domains recognize motifs other than proline-based sequences is unclear. In this study, we report SH3 domain binding to a novel proline-independent motif in immune cell adaptor SK...

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Détails bibliographiques
Auteurs principaux: Kang, Hyun, Freund, Christian, Duke-Cohan, Jonathan S., Musacchio, Andrea, Wagner, Gerhard, Rudd, Christopher E.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC203341/
https://ncbi.nlm.nih.gov/pubmed/10856234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.12.2889
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