DNA supercoiling enables the Type IIS restriction enzyme BspMI to recognise the relative orientation of two DNA sequences

Many proteins can sense the relative orientations of two sequences at distant locations in DNA: some require sites in inverted (head-to-head) orientation, others in repeat (head-to-tail) orientation. Like many restriction enzymes, the BspMI endonuclease binds two copies of its target site before cle...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Kingston, Isabel J., Gormley, Niall A., Halford, Stephen E.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2003
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12954757/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg743
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