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DNA supercoiling enables the Type IIS restriction enzyme BspMI to recognise the relative orientation of two DNA sequences

Many proteins can sense the relative orientations of two sequences at distant locations in DNA: some require sites in inverted (head-to-head) orientation, others in repeat (head-to-tail) orientation. Like many restriction enzymes, the BspMI endonuclease binds two copies of its target site before cle...

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Detalhes bibliográficos
Main Authors: Kingston, Isabel J., Gormley, Niall A., Halford, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC203326/
https://ncbi.nlm.nih.gov/pubmed/12954757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg743
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