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Rad52 and Ku bind to different DNA structures produced early in double-strand break repair

DNA double-strand breaks are repaired by one of two main pathways, non-homologous end joining or homologous recombination. A competition for binding to DNA ends by Ku and Rad52, proteins required for non-homologous end joining and homologous recombination, respectively, has been proposed to determin...

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Udgivet i:Nucleic Acids Res
Principais autores: Ristic, Dejan, Modesti, Mauro, Kanaar, Roland, Wyman, Claire
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203314/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12954758/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg729
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