Competition between the Rad50 Complex and the Ku Heterodimer Reveals a Role for Exo1 in Processing Double-Strand Breaks but Not Telomeres

The Mre11-Rad50-Nbs1(Xrs2) complex and the Ku70-Ku80 heterodimer are thought to compete with each other for binding to DNA ends. To investigate the mechanism underlying this competition, we analyzed both DNA damage sensitivity and telomere overhangs in Schizosaccharomyces pombe rad50-d, rad50-d pku7...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Tomita, Kazunori, Matsuura, Akira, Caspari, Thomas, Carr, Antony M., Akamatsu, Yufuko, Iwasaki, Hiroshi, Mizuno, Ken-ichi, Ohta, Kunihiro, Uritani, Masahiro, Ushimaru, Takashi, Yoshinaga, Koichi, Ueno, Masaru
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
DNA Dynamics and Chromosome Structure
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC165728/
https://ncbi.nlm.nih.gov/pubmed/12861005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.15.5186-5197.2003
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares