Biochemical evidence for Ku-independent backup pathways of NHEJ
Cells of higher eukaryotes process within minutes double strand breaks (DSBs) in their genome using a non-homologous end joining (NHEJ) apparatus that engages DNA-PKcs, Ku, DNA ligase IV, XRCC4 and other as of yet unidentified factors. Although chemical inhibition, or mutation, in any of these facto...
Gespeichert in:
| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2003
|
| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12954774/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg728 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|