Biochemical evidence for Ku-independent backup pathways of NHEJ

Cells of higher eukaryotes process within minutes double strand breaks (DSBs) in their genome using a non-homologous end joining (NHEJ) apparatus that engages DNA-PKcs, Ku, DNA ligase IV, XRCC4 and other as of yet unidentified factors. Although chemical inhibition, or mutation, in any of these facto...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Wang, Huichen, Perrault, Ange Ronel, Takeda, Yoshihiko, Qin, Wei, Wang, Hongyan, Iliakis, George
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2003
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12954774/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg728
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