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The Dcr2p phosphatase destabilizes Sic1p in Saccharomyces cerevisiae

Initiation of cell division is controlled by an irreversible switch. In Saccharomyces cerevisiae degradation of the Sic1p protein, an inhibitor of mitotic cyclin/cyclin-dependent kinase complexes, takes place before initiation of DNA replication, at a point called START. Sic1p is phosphorylated by m...

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Main Authors: Pathak, Ritu, Blank, Heidi M., Guo, Jinbai, Ellis, Sarah, Polymenis, Michael
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2031908/
https://ncbi.nlm.nih.gov/pubmed/17673172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.07.092
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