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The Unfolded Protein Response Is Not Necessary for the G1/S Transition, but It Is Required for Chromosome Maintenance in Saccharomyces cerevisiae

BACKGROUND: The unfolded protein response (UPR) is a eukaryotic signaling pathway, from the endoplasmic reticulum (ER) to the nucleus. Protein misfolding in the ER triggers the UPR. Accumulating evidence links the UPR in diverse aspects of cellular homeostasis. The UPR responds to the overall protei...

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Detalhes bibliográficos
Main Authors: Henry, Kelsey A., Blank, Heidi M., Hoose, Scott A., Polymenis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939067/
https://ncbi.nlm.nih.gov/pubmed/20856872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012732
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