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Gid8p (Dcr1p) and Dcr2p Function in a Common Pathway To Promote START Completion in Saccharomyces cerevisiae

How cells determine when to initiate DNA replication is poorly understood. Here we report that in Saccharomyces cerevisiae overexpression of the dosage-dependent cell cycle regulator genes DCR2 (YLR361C) and GID8 (DCR1/YMR135C) accelerates initiation of DNA replication. Cells lacking both GID8 and D...

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Detalhes bibliográficos
Main Authors: Pathak, Ritu, Bogomolnaya, Lydia M., Guo, Jinbai, Polymenis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539013/
https://ncbi.nlm.nih.gov/pubmed/15590836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.6.1627-1638.2004
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