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Gid8p (Dcr1p) and Dcr2p Function in a Common Pathway To Promote START Completion in Saccharomyces cerevisiae

How cells determine when to initiate DNA replication is poorly understood. Here we report that in Saccharomyces cerevisiae overexpression of the dosage-dependent cell cycle regulator genes DCR2 (YLR361C) and GID8 (DCR1/YMR135C) accelerates initiation of DNA replication. Cells lacking both GID8 and D...

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Autori principali: Pathak, Ritu, Bogomolnaya, Lydia M., Guo, Jinbai, Polymenis, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC539013/
https://ncbi.nlm.nih.gov/pubmed/15590836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.6.1627-1638.2004
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