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RNAi-mediated Abrogation of Cathepsin B and MMP-9 Gene Expression in a Malignant Meningioma Cell Line Leads to Decreased Tumor Growth, Invasion and Angiogenesis

Malignant meningiomas are highly aggressive and frequently recur after surgical resection of the tumor. Earlier studies have reported that the cysteine protease cathepsin B and the matrix metalloproteinase MMP-9 play important roles in tumor progression. In the present study, we made an attempt to e...

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Bibliografische gegevens
Hoofdauteurs: Tummalapalli, Padmaja, Spomar, Daniel, Gondi, Christopher S., Olivero, William C., Gujrati, Meena, Dinh, Dzung H., Rao, Jasti S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2031211/
https://ncbi.nlm.nih.gov/pubmed/17912429
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