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A Fluorescence Assay for Rapid Detection of Ligand Binding Affinity to HIV-1 gp41
The fusion-active conformation of the envelope protein gp41 of HIV-1 consists of an N-terminal trimeric α-helical coiled coil domain, and three anti-parallel C-terminal helices which fold down the grooves of the coiled coil to form a six-helix bundle. Disruption of the six-helix bundle is considered...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2030571/ https://ncbi.nlm.nih.gov/pubmed/16606347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/BC.2006.063 |
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