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NK cell survival mediated through the regulatory synapse with human DCs requires IL-15Rα

DCs activate NK cells during innate immune responses to viral infections. However, the composition and kinetics of the immunological synapse mediating this interaction are largely unknown. Here, we report the rapid formation of an immunological synapse between human resting NK cells and mature DCs....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brilot, Fabienne, Strowig, Till, Roberts, Susanne M., Arrey, Frida, Münz, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2030458/
https://ncbi.nlm.nih.gov/pubmed/17948125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31751
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