Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses

Dendritic cells (DCs) express many endocytic receptors that deliver antigens for major histocompatibility class (MHC) I and II presentation to CD8(+) and CD4(+) T cells, respectively. Here, we show that targeting Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) to one of them, the human multilecti...

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Bibliographische Detailangaben
Hauptverfasser: Gurer, Cagan, Strowig, Till, Brilot, Fabienne, Pack, Maggi, Trumpfheller, Christine, Arrey, Frida, Park, Chae Gyu, Steinman, Ralph M., Münz, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2008
Schlagworte:
Immunobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515117/
https://ncbi.nlm.nih.gov/pubmed/18519810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-148072
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