Targeting E2F1–DNA complexes with microgonotropen DNA binding agents

Microgonotropen (MGT) DNA binding drugs, which consist of an A+T-selective DNA minor groove binding tripyrrole peptide and polyamine chains attached to a central pyrrole that extend drug contact into the DNA major groove, were found to be extraordinarily effective inhibitors of E2 factor 1 (E2F1) as...

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Bibliografiska uppgifter
Huvudupphovsmän: Chiang, Shu-Yuan, Bruice, Thomas C., Azizkhan, Jane C., Gawron, Loretta, Beerman, Terry A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC20278/
https://ncbi.nlm.nih.gov/pubmed/9096302
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