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Dynamics of the Kv1.2 Voltage-Gated K(+) Channel in a Membrane Environment

All-atom molecular dynamics simulations are used to better understand the dynamic environment experienced by the Kv1.2 channel in a lipid membrane. The structure of the channel is stable during the trajectories. The pore domain keeps a well-defined conformation, whereas the voltage-sensing domains u...

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Bibliografiske detaljer
Main Authors: Jogini, Vishwanath, Roux, Benoît
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2025645/
https://ncbi.nlm.nih.gov/pubmed/17704179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.112540
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