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Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5(-/-) mice

Epithelial tubes represent fundamental building blocks of metazoan organisms; however, the mechanisms responsible for their formation and maintenance are not well understood. Here we show that unique and evolutionary conserved coiled-coil MAGUK protein, Dlg5, is required for epithelial tube maintena...

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Bibliografiske detaljer
Main Authors: Nechiporuk, Tamilla, Fernandez, Tania E., Vasioukhin, Valeri
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2023971/
https://ncbi.nlm.nih.gov/pubmed/17765678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.07.017
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