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Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice
Disruption of cell polarity is seen in many cancers; however, it is generally considered a late event in tumor progression. Lethal giant larvae (Lgl) has been implicated in maintenance of cell polarity in Drosophila and cultured mammalian cells. We now show that loss of Lgl1 in mice results in forma...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC374237/ https://ncbi.nlm.nih.gov/pubmed/15037549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1178004 |
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