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Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5(-/-) mice
Epithelial tubes represent fundamental building blocks of metazoan organisms; however, the mechanisms responsible for their formation and maintenance are not well understood. Here we show that unique and evolutionary conserved coiled-coil MAGUK protein, Dlg5, is required for epithelial tube maintena...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2023971/ https://ncbi.nlm.nih.gov/pubmed/17765678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.07.017 |
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