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A role for Pak protein kinases in Schwann cell transformation

Neurofibromatosis type 1 (NF1), a common autosomal dominant disorder caused by loss of the NF1 gene, is characterized clinically by neurofibromas and more rarely by neurofibrosarcomas. Neurofibromin, the protein encoded by NF1, possesses an intrinsic GTPase accelerating activity for the Ras proto-on...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Tang, Yi, Marwaha, Sunil, Rutkowski, J. Lynn, Tennekoon, Gihan I., Phillips, Peter C., Field, Jeffrey
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1998
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20227/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560242/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.5139
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