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A role for Pak protein kinases in Schwann cell transformation

Neurofibromatosis type 1 (NF1), a common autosomal dominant disorder caused by loss of the NF1 gene, is characterized clinically by neurofibromas and more rarely by neurofibrosarcomas. Neurofibromin, the protein encoded by NF1, possesses an intrinsic GTPase accelerating activity for the Ras proto-on...

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Main Authors: Tang, Yi, Marwaha, Sunil, Rutkowski, J. Lynn, Tennekoon, Gihan I., Phillips, Peter C., Field, Jeffrey
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC20227/
https://ncbi.nlm.nih.gov/pubmed/9560242
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