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A role for Pak protein kinases in Schwann cell transformation

Neurofibromatosis type 1 (NF1), a common autosomal dominant disorder caused by loss of the NF1 gene, is characterized clinically by neurofibromas and more rarely by neurofibrosarcomas. Neurofibromin, the protein encoded by NF1, possesses an intrinsic GTPase accelerating activity for the Ras proto-on...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Tang, Yi, Marwaha, Sunil, Rutkowski, J. Lynn, Tennekoon, Gihan I., Phillips, Peter C., Field, Jeffrey
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1998
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20227/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560242/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.5139
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