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A role for Pak protein kinases in Schwann cell transformation

Neurofibromatosis type 1 (NF1), a common autosomal dominant disorder caused by loss of the NF1 gene, is characterized clinically by neurofibromas and more rarely by neurofibrosarcomas. Neurofibromin, the protein encoded by NF1, possesses an intrinsic GTPase accelerating activity for the Ras proto-on...

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Detalhes bibliográficos
Main Authors: Tang, Yi, Marwaha, Sunil, Rutkowski, J. Lynn, Tennekoon, Gihan I., Phillips, Peter C., Field, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20227/
https://ncbi.nlm.nih.gov/pubmed/9560242
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