Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity

Here, we disrupted the p70 S6 kinase (p70(s6k)) gene in murine embryonic stem cells to determine the role of this kinase in cell growth, protein synthesis, and rapamycin sensitivity. p70(s6k−/−) cells proliferated at a slower rate than parental cells, suggesting that p70(s6k) has a positive influenc...

全面介紹

書目詳細資料

發表在:	Proc Natl Acad Sci U S A
Principais autores:	Kawasome, Hideki, Papst, Philip, Webb, Saiphone, Keller, Gordon M., Johnson, Gary L., Gelfand, Erwin W., Terada, Naohiro
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1998
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20208/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560223/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.5033
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!