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Association of calcium channel α(1S) and β(1a) subunits is required for the targeting of β(1a) but not of α(1S) into skeletal muscle triads

The skeletal muscle L-type Ca(2+) channel is a complex of five subunits that is specifically localized in the triad. Its primary function is the rapid activation of Ca(2+) release from cytoplasmic stores in a process called excitation-contraction coupling. To study the role of α(1S)–β(1a) interactio...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Neuhuber, Birgit, Gerster, Uli, Döring, Frank, Glossmann, Hartmut, Tanabe, Tsutomu, Flucher, Bernhard E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20205/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560220/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.5015
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