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Bax directly induces release of cytochrome c from isolated mitochondria

Bax is a pro-apoptotic member of the Bcl-2 protein family that resides in the outer mitochondrial membrane. It is controversial whether Bax promotes cell death directly through its putative function as a channel protein versus indirectly by inhibiting cellular regulators of the cell death proteases...

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Autori principali: Jürgensmeier, Juliane M., Xie, Zhihua, Deveraux, Quinn, Ellerby, Lisa, Bredesen, Dale, Reed, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC20202/
https://ncbi.nlm.nih.gov/pubmed/9560217
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