Bax directly induces release of cytochrome c from isolated mitochondria

Bax is a pro-apoptotic member of the Bcl-2 protein family that resides in the outer mitochondrial membrane. It is controversial whether Bax promotes cell death directly through its putative function as a channel protein versus indirectly by inhibiting cellular regulators of the cell death proteases...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Jürgensmeier, Juliane M., Xie, Zhihua, Deveraux, Quinn, Ellerby, Lisa, Bredesen, Dale, Reed, John C.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1998
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20202/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560217/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.4997
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