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Avoiding false-positive signals with nuclease-vulnerable molecular beacons in single living cells

There have been a growing number of studies where molecular beacons (MBs) are used to image RNA expression in living cells; however, the ability to make accurate measurements can be hampered by the generation of false-positive signals resulting from non-specific interactions and/or nuclease degradat...

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Main Authors: Chen, Antony K., Behlke, Mark A., Tsourkas, Andrew
格式: Artigo
語言:Inglês
出版: Oxford University Press 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2018645/
https://ncbi.nlm.nih.gov/pubmed/17702767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm593
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