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Ratiometric bimolecular beacons for the sensitive detection of RNA in single living cells

Numerous studies have utilized molecular beacons (MBs) to image RNA expression in living cells; however, there is growing evidence that the sensitivity of RNA detection is significantly hampered by their propensity to emit false-positive signals. To overcome these limitations, we have developed a ne...

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Autori principali: Chen, Antony K., Davydenko, Olga, Behlke, Mark A., Tsourkas, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919734/
https://ncbi.nlm.nih.gov/pubmed/20507905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq436
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