Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor

The x-ray structures of an inhibitor complex of the catalytic core domain of avian sarcoma virus integrase (ASV IN) were solved at 1.9- to 2.0-Å resolution at two pH values, with and without Mn(2+) cations. This inhibitor (Y-3), originally identified in a screen for inhibitors of the catalytic activ...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Lubkowski, Jacek, Yang, Fan, Alexandratos, Jerry, Wlodawer, Alexander, Zhao, He, Burke, Terrence R., Neamati, Nouri, Pommier, Yves, Merkel, George, Skalka, Anna Marie
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1998
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC20173/
https://ncbi.nlm.nih.gov/pubmed/9560188
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы