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Population PK and PK/PD modelling of microencapsulated octreotide acetate in healthy subjects

AIMS: To develop a population model that can describe the pharmacokinetic profile of microencapsulated octreotide acetate in healthy cholecystectomized subjects. To investigate the correlation between serum IGF-1 and octreotide concentration. METHODS: A population pharmacokinetic analysis was perfor...

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Main Authors: Zhou, Honghui, Chen, Tian-Ling, Marino, Mark, Lau, Henry, Miller, Thomas, Kalafsky, Gaetana, McLeod, James F
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2015017/
https://ncbi.nlm.nih.gov/pubmed/11136293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00297.x
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