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Effect of rifampicin on the pharmacokinetics and pharmacodynamics of glimepiride

AIMS: To study the effects of rifampicin on the pharmacokinetics and pharmaco-dynamics of glimepiride, a new sulphonylurea antidiabetic drug. METHODS: In this randomised, two-phase cross-over study, 10 healthy volunteers were treated for 5 days with 600 mg rifampicin or placebo once daily. On day 6,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Niemi, Mikko, Kivistö, Kari T, Backman, Janne T, Neuvonen, Pertti J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2015006/
https://ncbi.nlm.nih.gov/pubmed/11136298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00295.x
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