Comparison of the vasoconstrictor effects of the selective 5-HT(1D)-receptor agonist L-775,606 with the mixed 5-HT(1B)/(1D)-receptor agonist sumatriptan and 5-HT in human isolated coronary artery

AIMS: Vasoconstriction in human coronary artery can be mediated via activation of both 5-HT(2) and 5-HT(1B)-receptors. Coronary vasoconstriction is a rare, but potential adverse effect of the antimigraine drug sumatriptan. In order to investigate the receptor population involved we compared the vaso...

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Detalhes bibliográficos
Main Authors: Longmore, J, Maguire, J J, MacLeod, A, Street, L, Schofield, W N, Hill, R G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014896/
https://ncbi.nlm.nih.gov/pubmed/10671906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00129.x
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