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Gi-Protein Coupled 5-HT(1B/D) Receptor Agonist Sumatriptan Induces Type I Hyperalgesic Priming
We have recently described a novel form of hyperalgesic priming (type II) induced by agonists at two clinically important Gi-protein coupled receptors (Gi-GPCRs), mu-opioid and A1-adenosine. Like mu-opioids, the anti-migraine triptans, which act at 5-HT(1B/D) Gi-GPCRs have been implicated in pain ch...
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| Publicado no: | Pain |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048915/ https://ncbi.nlm.nih.gov/pubmed/27075428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000581 |
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