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Effect of caffeine on clozapine pharmacokinetics in healthy volunteers

AIMS: To assess the effects of caffeine on the pharmacokinetics of clozapine in healthy volunteers. METHODS: This was an open label randomized crossover study in 12 nonsmoking healthy male volunteers. The subjects received a single oral dose of 12.5 mg clozapine in each phase with or without concomi...

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Bibliografske podrobnosti
Main Authors: Hägg, Staffan, Spigset, Olav, Mjörndal, Tom, Dahlqvist, Rune
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014893/
https://ncbi.nlm.nih.gov/pubmed/10606838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00111.x
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