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Non-linear fluvoxamine disposition

AIMS: To study the pharmacokinetics of fluvoxamine when given in increasing doses to healthy volunteers. METHODS: Ten healthy, non-smoking men were given maintenance treatment with fluvoxamine for 4 weeks. Eight subjects were CYP2D6 extensive metabolisers (EMs) and two were CYP2D6 poor metabolisers...

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Main Authors: Spigset, Olav, Granberg, Kerstin, Hägg, Staffan, Söderström, Emma, Dahlqvist, Rune
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873375/
https://ncbi.nlm.nih.gov/pubmed/9517369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00670.x
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