Population pharmacokinetics of tolcapone in parkinsonian patients in dose finding studies

AIMS: To use pharmacostatistical models to characterize tolcapone's pharmacokinetics in parkinsonian patients, and to identify any demographic subpopulations which may be at risk of either under- or over-exposure to this catechol-O-methyltransferase (COMT) inhibitor. METHODS: Four hundred and t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Jorga, Karin, Fotteler, Bärbel, Banken, Ludger, Snell, Paul, Steimer, Jean-Louis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2000
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014884/
https://ncbi.nlm.nih.gov/pubmed/10606836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00113.x
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